Hey friends / patients,
The last couple of years, there's been some discussion of risk of osteonecrosis (the patient's bone breaking down and not healing well) if the patient is on Fosamax-type drugs and they have dental surgery, and extraction or maybe implants placed.
When talking with dental friends, it was kind of odd to us, because very few of us had even seen one case of osteonecrosis. Yet, there was all of this worry that it could happen.
Here's a new study that shows a VERY LOW chance of problems with healing in patients taking Fosamax-type drugs. The new report shows a prevalence of Osteonecrosis of the Jaw in Patients Using Fosamax®-type Drugs is 0.1%.
According to a large scale study carried out in California, osteonecrosis of the jaw (ONJ) occurred in 1 out of 952 survey respondents taking oral bisphosphonates for prevention of osteoporosis. One out of 952 represents a prevalence rate of 0.1%. This data provides new information to be added to previous reports describing the prevalence of this condition in users of Fosamax-type drugs.
What's this mean? Women who are taking Fosamax-type drugs don't appear to have risk of poor healing if they have a tooth extraction, a dental implant or dental surgery.
Best,
Dr. Ron Receveur
Monday
Saturday
Mother's Gum Disease Linked to Baby's Death!
Dear Friends:
We've known for a long time that the health of your mouth was linked to Heart Disease. This new revelation CHANGES EVERYTHING! This article is a MUST READ!
First Oral Bacteria Found Linking a Mother and Her Stillborn Baby
ScienceDaily (Jan. 22, 2010) — Yiping Han, a researcher from Department of Periodontics at Case Western Reserve University School of Dental Medicine, reports the first documented link between a mother with pregnancy-associated gum disease to the death of her fetus. The findings are discussed in the February issue of Obstetrics & Gynecology.
An Internet search in 2008 led a friend of a mother, who had just delivered a stillborn baby, to Han's research lab -- one of the few in the world working on understanding the role variations of the oral bacteria, Fusobacterium nucleatum, have on pre-term labor and stillbirths. The mother delivered her full-term baby at Saint John's Health Center in Santa Monica, Calif., at 39 weeks and five days.
During the 35-year-old mother's pregnancy (her first), she told Han she experienced excessive gum bleeding, a symptom of pregnancy-associated gingivitis. Approximately 75 percent of pregnant women experience gum bleeding due to the hormonal changes during pregnancy.
"There is an old wives' tale that you lose a tooth for each baby, and this is due to the underlying changes during pregnancy," said Han, "but if there is another underlying condition in the background, then you may lose more than a tooth but a baby."
Bleeding associated with the gingivitis allowed the bacteria, normally contained to the mouth because of the body's defense system, to enter the blood and work its way to the placenta. Even though the amniotic fluid was not available for testing, Han suspects from work with animal models that the bacteria entered the immune-free amniotic fluid and eventually ingested by the baby. Han says normally a mother's immune system takes care of the bacteria in the blood before it reaches the
placenta. But in this case, the mother also experienced an upper respiratory infection like a cold and low-grade fever just a few days before the stillbirth.
"The timing is important here because it fits the time frame of hematogenous (through the blood)spreading we observed in animals," Han said.
Postmortem microbial studies of the baby found the presence of F. nucleatum in the lungs and stomach. The baby had died from a septic infection and inflammation caused by bacteria. After questioning the mother about her health during the pregnancy, Han arranged for her to visit a periodontist, who collected plaque samples from her teeth.
Using DNA cloning technologies, Han found a match in the bacterium in the mother's mouth with the bacterium in the baby's infected lungs and stomach. Han also ruled out by testing bacteria from the vaginal and rectal areas, which did not show the presence of F. nucleatum.
"The testing strongly suggested the bacteria were delivered through the blood," Han said. With preventative periodontal treatment and oral health care, the mother has since given birth to a healthy baby. Han, who has spent the past decade taking her oral bacteria research from the lab to the bedside, says this points again to the growing importance of good oral health care. In addition to this direct link from the mother to her baby, oral bacteria have been associated with heart disease, diabetes and arthritis.
The researcher suggests women, who are considering a pregnancy, seek dental care to take care of any oral health problems before getting pregnant. If pregnant, she encourages expectant moms to practice good oral health and alert the doctor to any gum bleeding.
Collaborating with Han on the case study were Yann Fardini, Casey Chen, Karla G. Iacampo, Victoria A. Peraino, Jaime Shamonki and Raymond W. Redline. The study had support from the National Institute of Dental and Craniofacial Research.
We've known for a long time that the health of your mouth was linked to Heart Disease. This new revelation CHANGES EVERYTHING! This article is a MUST READ!
First Oral Bacteria Found Linking a Mother and Her Stillborn Baby
ScienceDaily (Jan. 22, 2010) — Yiping Han, a researcher from Department of Periodontics at Case Western Reserve University School of Dental Medicine, reports the first documented link between a mother with pregnancy-associated gum disease to the death of her fetus. The findings are discussed in the February issue of Obstetrics & Gynecology.
An Internet search in 2008 led a friend of a mother, who had just delivered a stillborn baby, to Han's research lab -- one of the few in the world working on understanding the role variations of the oral bacteria, Fusobacterium nucleatum, have on pre-term labor and stillbirths. The mother delivered her full-term baby at Saint John's Health Center in Santa Monica, Calif., at 39 weeks and five days.
During the 35-year-old mother's pregnancy (her first), she told Han she experienced excessive gum bleeding, a symptom of pregnancy-associated gingivitis. Approximately 75 percent of pregnant women experience gum bleeding due to the hormonal changes during pregnancy.
"There is an old wives' tale that you lose a tooth for each baby, and this is due to the underlying changes during pregnancy," said Han, "but if there is another underlying condition in the background, then you may lose more than a tooth but a baby."
Bleeding associated with the gingivitis allowed the bacteria, normally contained to the mouth because of the body's defense system, to enter the blood and work its way to the placenta. Even though the amniotic fluid was not available for testing, Han suspects from work with animal models that the bacteria entered the immune-free amniotic fluid and eventually ingested by the baby. Han says normally a mother's immune system takes care of the bacteria in the blood before it reaches the
placenta. But in this case, the mother also experienced an upper respiratory infection like a cold and low-grade fever just a few days before the stillbirth.
"The timing is important here because it fits the time frame of hematogenous (through the blood)spreading we observed in animals," Han said.
Postmortem microbial studies of the baby found the presence of F. nucleatum in the lungs and stomach. The baby had died from a septic infection and inflammation caused by bacteria. After questioning the mother about her health during the pregnancy, Han arranged for her to visit a periodontist, who collected plaque samples from her teeth.
Using DNA cloning technologies, Han found a match in the bacterium in the mother's mouth with the bacterium in the baby's infected lungs and stomach. Han also ruled out by testing bacteria from the vaginal and rectal areas, which did not show the presence of F. nucleatum.
"The testing strongly suggested the bacteria were delivered through the blood," Han said. With preventative periodontal treatment and oral health care, the mother has since given birth to a healthy baby. Han, who has spent the past decade taking her oral bacteria research from the lab to the bedside, says this points again to the growing importance of good oral health care. In addition to this direct link from the mother to her baby, oral bacteria have been associated with heart disease, diabetes and arthritis.
The researcher suggests women, who are considering a pregnancy, seek dental care to take care of any oral health problems before getting pregnant. If pregnant, she encourages expectant moms to practice good oral health and alert the doctor to any gum bleeding.
Collaborating with Han on the case study were Yann Fardini, Casey Chen, Karla G. Iacampo, Victoria A. Peraino, Jaime Shamonki and Raymond W. Redline. The study had support from the National Institute of Dental and Craniofacial Research.
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